drugset / Trial / NCT00889538
Study of Glutathione, Vitamin C and Cysteine in Children With Autism and Severe Behavior Problems
Completed
24 enrolled
University of Louisville
Cumberland Pharmaceuticals · collabNorton Healthcare · collab
RandomizedCrossoverQuadruple-blindTreatment
Summary
This is a double-blind, placebo-controlled crossover study to evaluate the safety and efficacy of glutathione alone or glutathione, vitamin C and NAC treatment in children with autism who also have severe behavior problems. The investigators hypothesis is that children with autism will show improvement in both learning capabilities and behavior with either glutathione, or glutathione, vitamin C and NAC therapy.
Timeline
- Start
- 2009-04
- Primary completion
- 2012-09
- Completion
- 2012-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Glutathione | Peptide | 600 mg | Intravenous |
| Comparator | N-acetylcysteine | Small molecule | 20 mg/kg | Intravenous |
| Comparator | Vitamin C | Other / unclassified | 2000 mg | Intravenous |