drugset / Trial / NCT00890500
Safety and Efficacy of ProHema Modulated Umbilical Cord Blood Units in Subjects With Hematologic Malignancies.
Non-randomizedFactorialOpen-labelTreatment
Summary
The purpose of this research study is to determine the safety and efficacy of a reduced intensity conditioning regimen during a double umbilical cord blood unit transplant with one of the cord blood units modulated with ProHema.
Timeline
- Start
- 2011-01
- Primary completion
- 2013-05
- Completion
- 2013-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | ANTILYMPHOCYTE IMMUNOGLOBULIN (HORSE) | Protein / enzyme biologic | 1 mg/kg | — |
| Comparator | Fludarabine | Small molecule | 30 mg/m2 | Intravenous |
| Comparator | Melphalan | Small molecule | 100 mg/m2 | Intravenous |
| Comparator | Sirolimus | Small molecule | — | — |
| Comparator | Tacrolimus | Small molecule | — | — |