drugset / Trial / NCT00901303

Pilot Study of Abbreviated Chemotherapy Based on Positron Emission Tomography (PET) Scan in Hodgkin's Lymphoma

NCT00901303

Non-randomizedSingle-groupOpen-labelTreatment

Summary

The primary objective of the study is to determine the progression-free survival \[PFS\] at 36 months for patients with Hodgkin lymphoma who achieve a complete metabolic response as demonstrated by a negative fluorodeoxyglucose (FDG)-PET scan after one cycle of ABVD (adriamycin, bleomycin, vinblastine, dacarbazine) who undergo abbreviated ABVD chemotherapy (3 cycles).

Timeline

Start
2008-10
Primary completion
2010-06
Completion
2011-05-23

Drugs

EvaluationDrugModalityDoseRoute
Subject Bleomycin Unknown 10 unknown
Subject Dacarbazine Small molecule 375 unknown
Subject Doxorubicin Other / unclassified 25 mg/m2
Subject Vinblastine Small molecule 6 mg/m2

Indications