Pharmacokinetics of AP214 Acetate in Patients Undergoing Cardiac Surgery

Summary

The purpose of the present research study is to investigate the pharmacokinetics, as well as safety, tolerability and pharmacodynamics of different ascending dosing regimens of AP214 in patients undergoing cardiac surgery. AP214, the investigational drug, is being developed to potentially prevent post-surgical kidney injury after thoracic aortic aneurysm repair.

Timeline

Start

2009-05

Primary completion

2010-06

Completion

2010-06

Drugs

Indications