drugset / Trial / NCT00903942

Abraxane and RT for Non-Small Cell Lung Cancer (NSCLC)

NCT00903942 ↗

Non-randomizedSingle-groupOpen-labelTreatment

Summary

For patients with stage III Lung Cancer, We propose one cycle chemotherapy using Abraxane and Carboplatin, followed by pulsed low-dose sensitizing Abraxane chemotherapy and daily Radiation. This will be followed by more hi-dose chemotherapy. We anticipate this regimen to target early distant microscopic spread by using one cycle of chemotherapy prior to radiation, and to achieve control of the disease in the lung by combining pulsed low-dose sensitizing Abraxane, with radiation.

Timeline

Start
2008-03
Primary completion
2012-03
Completion
—

Outcome

Outcome not reported

Stopped (Business): “funding was withdrawn from Drug company”

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule 6 unknown —
Subject Paclitaxel Small molecule 20 mg/m2 —
Subject Paclitaxel Small molecule 30 mg/m2 —
Subject Paclitaxel Small molecule 260 mg/m2 —