A Trial of Oral Misoprostol for Labor Augmentation

Phase 4 Completed 350 enrolled University of Texas Southwestern Medical Center

RandomizedParallel-groupOpen-labelTreatment

Summary

This is a prospective, randomized, controlled trial designed to examine the efficacy of oral misoprostol for labor augmentation compared to a standard regimen of intravenous oxytocin.

Timeline

Start: 2008-12
Primary completion: 2011-01
Completion: 2011-01

Publications

Bleich AT, Villano KS, Lo JY, Alexander JM, McIntire DD, Leveno KJ. Oral misoprostol for labor augmentation: a randomized controlled trial. Obstet Gynecol. 2011 Dec;118(6):1255-1260. doi: 10.1097/AOG.0b013e318236df5b.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Misoprostol	Other / unclassified	75 ug	Oral
Comparator	Oxytocin	Peptide	—	Intravenous

Indications

No indication recorded.