drugset / Trial / NCT00911651
Study to Assess the Effect of Salbutamol and Ipratropium Bromide in Chronic Obstructive Pulmonary Disease (COPD) Patients
RandomizedCrossoverOpen-labelTreatment
Summary
The objectives of this study are to assess the effect of salbutamol in comparison with ipratropium bromide on the geometry of central and peripheral airways and to correlate spirometric indices with the Computational Fluid Dynamics (CFD) based calculated airway volumes and resistances for both compounds.
Timeline
- Start
- 2008-06
- Primary completion
- 2008-07
- Completion
- 2008-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ipratropium | Small molecule | 80 ug | Inhaled |
| Comparator | Salbutamol | Unknown | 400 ug | Inhaled |