drugset / Trial / NCT00911651

Study to Assess the Effect of Salbutamol and Ipratropium Bromide in Chronic Obstructive Pulmonary Disease (COPD) Patients

NCT00911651

RandomizedCrossoverOpen-labelTreatment

Summary

The objectives of this study are to assess the effect of salbutamol in comparison with ipratropium bromide on the geometry of central and peripheral airways and to correlate spirometric indices with the Computational Fluid Dynamics (CFD) based calculated airway volumes and resistances for both compounds.

Timeline

Start
2008-06
Primary completion
2008-07
Completion
2008-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ipratropium Small molecule 80 ug Inhaled
Comparator Salbutamol Unknown 400 ug Inhaled