Donepezil Treatment for Sleep Apnea Patients

Phase 4 Unknown 60 enrolled Associacao Fundo de Incentivo a Psicofarmcologia Fundação de Amparo à Pesquisa do Estado de São Paulo · collab

RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to determine the effects of the anticholinesterase drug donepezil on sleep apnea patients. Sleep structure and respiratory parameters will be analyzed by polysomnography.

Timeline

Start: 2007-03
Primary completion: 2009-12
Completion: 2009-12

Publications

Sukys-Claudino L, Moraes W, Guilleminault C, Tufik S, Poyares D. Beneficial effect of donepezil on obstructive sleep apnea: a double-blind, placebo-controlled clinical trial. Sleep Med. 2012 Mar;13(3):290-6. doi: 10.1016/j.sleep.2011.09.014. Epub 2012 Jan 26.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Donepezil	Small molecule	10 mg	—

Donepezil Treatment for Sleep Apnea Patients

Summary

Timeline

Publications

Drugs

Indications