drugset / Trial / NCT00919776
Ciclosporin in the Management of Chronic or Recurrent Erythema Nodosum Leprosum
Phase 2
Completed
20 enrolled
London School of Hygiene and Tropical Medicine
Alert Hospital, Ethiopia · collabArmauer Hansen Research Institute, Ethiopia · collabHomes and Hospitals of St Giles · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
Study 2B: Ciclosporin in the management of chronic or recurrent Erythema Nodosum Leprosum Aim: To assess the safety, tolerability and efficacy of Ciclosporin in the treatment of patients whose ENL is not controlled with standard Prednisolone. Objective: A pilot double blind controlled study randomizing patients whose ENL is not controlled with standard Prednisolone, and comparing a group treated with Ciclosporin to a group treated with additional steroid only.
Timeline
- Start
- 2010-08
- Primary completion
- 2012-12
- Completion
- 2013-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclosporine | Peptide | 7.5 mg/kg | — |
| Comparator | Prednisolone | Other / unclassified | 40 mg | — |