drugset / Trial / NCT00922129

Effectiveness of Conversion to Sirolimus Versus Calcineurin Inhibitor (CNI) Reduction in Renal Transplant Patients With Prostate Cancer

NCT00922129

Phase 2/3 Withdrawn St. Joseph's Healthcare Hamilton
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the role and effectiveness of conversion to sirolimus versus CNI reduction in renal transplant patients with prostate cancer.

Timeline

Start
2009-09
Primary completion
2011-01
Completion
2011-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cyclosporine Peptide 3 mg/kg Oral
Comparator Cyclosporine Peptide 4 mg/kg Oral
Subject Sirolimus Small molecule 5 mg Oral
Comparator Tacrolimus Small molecule 0.038 mg/kg Oral
Comparator Tacrolimus Small molecule 0.045 mg/kg Oral

Indications