drugset / Trial / NCT00933309
The Impact of Obesity and Obesity Treatments on Breast Cancer
Phase 1
Completed
25 enrolled
M.D. Anderson Cancer Center
Susan G. Komen Breast Cancer Foundation · collab
RandomizedSingle-groupOpen-labelTreatment
Summary
The goal of this clinical research study is to find the highest tolerable dose of Avandamet that can be given in combination with exemestane to patients who are obese and postmenopausal with hormone-receptive-positive breast cancer that has spread to other parts of the body.
Timeline
- Start
- 2009-07
- Primary completion
- 2012-08
- Completion
- 2012-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Exemestane | Small molecule | 25 mg | Oral |
| Subject | Metformin | Small molecule | 500 mg | Oral |
| Subject | Rosiglitazone | Small molecule | 2 mg | Oral |