drugset / Trial / NCT00939510

Lenalidomide and GM-CSF in Treating Patients With Prostate Cancer

NCT00939510

NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Lenalidomide may stop the growth of prostate cancer by blocking blood flow to the tumor. GM-CSF may stimulate the immune system in different ways and stop tumor cells from growing. Giving lenalidomide together with GM-CSF may kill more tumor cells. PURPOSE: This phase I/II trial is studying the side effects and best dose of lenalidomide when given together with GM-CSF and to see how well it works in treating patients with prostate cancer.

Timeline

Start
2005-07
Primary completion
2009-10
Completion
2012-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Lenalidomide Other / unclassified 25 mg Oral
Background sargramostim Protein / enzyme biologic 250 ug Subcutaneous

Indications