drugset / Trial / NCT00941330

Exemestane or Docetaxel-Cytoxan in Low Recurrence Score Cancers

NCT00941330

Phase 2 Completed 31 enrolled Emory University Pfizer · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

The patients are being asked to take part in this study because they have a hormone receptor-positive breast cancer (contains estrogen and/or progesterone receptors) and their doctor has told them that they have an option to receive chemotherapy or hormonal therapy before surgery. The purpose of this study is to assess if chemotherapy using docetaxel and cytoxan (TC) or hormonal therapy using exemestane can shrink the size of their breast tumor and allow them to preserve the breast or have less extensive surgery on their breast.

Timeline

Start
2009-07
Primary completion
2015-05
Completion
2015-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cyclophosphamide Other / unclassified 600 mg/m2 Intravenous
Comparator Docetaxel Small molecule 75 mg/m2 Intravenous
Subject Exemestane Small molecule 25 mg Oral

Indications