drugset / Trial / NCT00945763
Single Dose Study of N1539 in the Treatment of Pain Secondary to Dental Impaction Surgery
RandomizedParallel-groupQuadruple-blindTreatment
Summary
To evaluate the safety and efficacy of single IV doses of N1539 after dental impaction surgery.
Timeline
- Start
- 2009-07
- Primary completion
- 2009-11
- Completion
- 2009-11
Publications
- Viscusi ER, Gan TJ, Bergese S, Singla N, Mack RJ, McCallum SW, Du W, Hobson S. Intravenous meloxicam for the treatment of moderate to severe acute pain: a pooled analysis of safety and opioid-reducing effects. Reg Anesth Pain Med. 2019 Mar;44(3):360-368. doi: 10.1136/rapm-2018-100184. Epub 2019 Feb 7.
- Christensen SE, Cooper SA, Mack RJ, McCallum SW, Du W, Freyer A. A Randomized Double-Blind Controlled Trial of Intravenous Meloxicam in the Treatment of Pain Following Dental Impaction Surgery. J Clin Pharmacol. 2018 May;58(5):593-605. doi: 10.1002/jcph.1058. Epub 2018 Jan 12.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ibuprofen | Small molecule | 400 mg | Oral |
| Subject | Meloxicam | Small molecule | 15 mg | Intravenous |
| Subject | Meloxicam | Small molecule | 30 mg | Intravenous |
| Subject | Meloxicam | Small molecule | 60 mg | Intravenous |
Indications
No indication recorded.