drugset / Trial / NCT00950885

Melatonin Treatment for Induced Transient Insomnia

NCT00950885

Completed 42 enrolled Brigham and Women's Hospital
RandomizedParallel-groupTriple-blindBasic science

Summary

Melatonin supplements have been reported to be an effective treatment for circadian rhythm sleep disorders, including shift work dyssomnia, jet-lag, delayed sleep phase syndrome, and sleep disruption suffered by many blind individuals. However, the mechanism(s) by which melatonin affects the timing of sleep are not well-understood. The purpose of this study is to determine if melatonin improves sleep and performance on a schedule simulating eastward travel. This study will provide information regarding the mechanism of action of melatonin that will be critical for the use of melatonin as a treatment for circadian rhythm sleep disorders.

Timeline

Start
2009-09
Primary completion
2013-08
Completion
2013-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Melatonin Small molecule 0.5 mg
Subject Melatonin Small molecule 3 mg