The Effect of Welchol on Glucose Metabolism in Type 2 Diabetics

Phase 4 Completed 38 enrolled Mayo Clinic Daiichi Sankyo · collab National Center for Research Resources (NCRR) · collab National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · collab

RandomizedParallel-groupQuadruple-blindBasic science

Summary

The goal of this study was to determine the metabolic mechanism for a certain type medication's ability to lower blood sugar after a meal in Type 2 Diabetics, in order to develop a better understanding of it's potential role in the treatment of obesity.

Timeline

Start: 2009-08
Primary completion: 2012-07
Completion: 2012-12

Publications

Results Smushkin G, Sathananthan M, Piccinini F, Dalla Man C, Law JH, Cobelli C, Zinsmeister AR, Rizza RA, Vella A. The effect of a bile acid sequestrant on glucose metabolism in subjects with type 2 diabetes. Diabetes. 2013 Apr;62(4):1094-101. doi: 10.2337/db12-0923. Epub 2012 Dec 18.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Colesevelam	Other / unclassified	1875 mg	Oral
Background	Metformin	Small molecule	500 mg	Oral

The Effect of Welchol on Glucose Metabolism in Type 2 Diabetics

Summary

Timeline

Publications

Drugs

Indications