drugset / Trial / NCT00953771
Safety Study of Danazol With Plasma Exchange and Steroids for the Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Phase 2
Terminated
9 enrolled
Icahn School of Medicine at Mount Sinai
Beth Israel Medical Center · collab
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The purpose of the study is to find out if administration of danazol with plasma exchange and corticosteroids will reduce the number of plasma exchanges required to control Thrombotic Thrombocytopenic Purpura (TTP).
Timeline
- Start
- 2008-10
- Primary completion
- 2015-11-19
- Completion
- 2015-11-19
Publications
- Results Torri V, Friedman M, Shapira I, Patel AA, Yoe J, Shah VP, Mirzoyev T, Machuca M, Varma M. Phase II study of danazol with plasma exchange and corticosteroids for the treatment of thrombotic thrombocytopenic purpura. Blood (2023) 142 (Supplement 1): 4007.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Danazol | Other / unclassified | 600 mg | Oral |