Etoricoxib in Acute Ankle Ligament Sprains

Phase 4 Withdrawn University of Cape Town Merck Sharp & Dohme LLC · collab

RandomizedParallel-groupTriple-blindTreatment

Summary

The aim of the study is to measure the effectiveness of treatment over 7 days with commonly used anti-inflammatory medications namely etoricoxib and diclofenac (Voltaren) on reducing the severity of pain, swelling and loss of function (range of movement, proprioception) arising from a mild to moderate sprain (partial tear) of the lateral (outer) ligaments of the ankle joint. This injury is commonly known as an ankle sprain.

Timeline

Start: 2009-11
Primary completion: 2010-12
Completion: 2011-07

Publications

Jones P, Lamdin R, Dalziel SR. Oral non-steroidal anti-inflammatory drugs versus other oral analgesic agents for acute soft tissue injury. Cochrane Database Syst Rev. 2020 Aug 12;8(8):CD007789. doi: 10.1002/14651858.CD007789.pub3.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Diclofenac	Other / unclassified	50 mg	—
Subject	Etoricoxib	Small molecule	120 mg	—

Indications

No indication recorded.