drugset / Trial / NCT00957853
Preoperative Treatment With Cetuximab and/or IMC-A12
RandomizedParallel-groupOpen-labelTreatment
Summary
The goal of this clinical research study is to give cetuximab and/or IMC-A12 before surgery for squamous cell carcinoma of the head and neck, in order to learn if these study drugs may cause changes in biomarkers. Biomarkers are chemical "markers" in the blood and/or tissue that may be related to a reaction to study treatment. The safety of the study treatments will also be studied.
Timeline
- Start
- 2011-10-17
- Primary completion
- 2018-08-15
- Completion
- 2018-08-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cetuximab | Monoclonal antibody | 250 mg/m2 | Intravenous |
| Subject | Cixutumumab | Monoclonal antibody | 6 mg/kg | Intravenous |