drugset / Trial / NCT00958854

Fludarabine, Cyclophosphamide, and Thalidomide in Treating Patients With Angioimmunoblastic T-Cell Lymphoma

NCT00958854 ↗

Phase 2 Unknown 37 enrolled Cancer Research UK
Open-labelTreatment

Summary

RATIONALE: Drugs used in chemotherapy, such as fludarabine and cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Thalidomide may stop the growth of lymphoma by blocking blood flow to the cancer. Giving fludarabine and cyclophosphamide together with thalidomide may kill more cancer cells. PURPOSE: This phase II trial is studying how well giving fludarabine and cyclophosphamide together with thalidomide works in treating patients with angioimmunoblastic T-cell lymphoma.

Timeline

Start
2006-01
Primary completion
2012-03
Completion
—

Drugs

EvaluationDrugModalityDoseRoute
Subject Cyclophosphamide Other / unclassified — Oral
Subject Fludarabine Small molecule — Oral
Subject Thalidomide Other / unclassified — Oral

Indications