drugset / Trial / NCT00960297

Preoperative Chemotherapy and Bevacizumab in Patients With Stage IB (>4 cm), II, or Select Stage III NSCLC

NCT00960297 ↗

NaSingle-groupOpen-labelTreatment

Summary

The rationale for this multicenter, phase II trial is to examine the impact of carboplatin/paclitaxel with bevacizumab in the preoperative treatment of patients with stage IB (\> 4.0 cm), II, and select stage III NSCLC. If this novel regimen proves to be safe and active in this setting, this would provide rationale for further investigation in a larger, prospective, randomized setting.

Timeline

Start
2009-08
Primary completion
2012-11
Completion
2013-05

Outcome

Outcome not reported

Stopped (Enrollment): “Study was terminated due to slow accrual”

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 15 mg/kg Intravenous
Subject Carboplatin Small molecule 6 unknown Intravenous
Subject Paclitaxel Small molecule 200 mg/m2 Intravenous