Ezetimibe in Patients Hypo-responsive to Statins

Summary

Response to statin therapy for elevated low density lipoprotein is variable and may be influenced by cholesterol absorption. This study will evaluate whether combination therapy with atorvastatin/ezetimibe will be superior to atorvastatin alone in subjects who have less than 25% LDL reduction on starting dose statin (eg, atorvastatin 10 mg daily or simvastatin 20 mg daily).

Timeline

Start

2009-09

Primary completion

2011-09

Completion

2012-09

Drugs

Indications