drugset / Trial / NCT00965107
Onset Time of Thiopental Versus Propofol in the Elderly
RandomizedParallel-groupTriple-blindTreatment
Summary
This study is aimed at increasing the safety of the use of anaesthesia in an elderly population (\> 60 years). Patients with decreased physiological reserve, including all elderly patients, have an increased risk of getting an erroneous induction bolus. This project will investigate how fast elderly patients (\> 60 years) fall asleep during bolus induction of anaesthesia with two of the most used hypnotics, thiopental and propofol, evaluated with BIS-monitoring and clinical signs of anaesthetic depth. The hemodynamic response will also be evaluated.
Timeline
- Start
- 2009-09
- Primary completion
- 2010-03
- Completion
- 2010-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propofol | Small molecule | 1 mg/kg | — |
| Subject | Thiopental | Small molecule | 2.5 mg/kg | — |
Indications
No indication recorded.