Drugs / Thiopental
Thiopental
also known as
Thiopental Sodium · pentothal sodium · Farmotal · Hypnostan · Intraval sod · Leopental · Nesdonal · NSC-759557 · +14 more
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | PENTOTHAL | — | 1959-09-23 | fda.gov ↗ |
Trials 9
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT00142493 | Sep 2004 → Aug 2008 | amnestic disorder | Memorial Sloan Kettering Cancer Center | Completed | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT00478907 | Mar 2004 → Mar 2006 | strabismus | Isfahan University of Medical Sciences | Completed | No outcome recorded |
| Phase 2 | NCT01140100 | — | — | Shiraz University of Medical Sciences | Completed | No outcome recorded |
| Phase 42 trials | ||||||
| Phase 4 | NCT02809378 | Jun 2016 → Apr 2017 | — | Ajou University School of Medicine | Completed | No outcome recorded |
| Phase 4 | NCT00965107 | Sep 2009 → Mar 2010 | — | Rigshospitalet, Denmark | Completed | No outcome recorded |
| Phase not applicable4 trials · 1 missed | ||||||
| — | NCT07596095 | Jul 2024 → Dec 2025 | — | Dr. Lutfi Kirdar Kartal Training and Research Hospital | Completed | No outcome recorded |
| — | NCT02056236 | Apr 2014 → Apr 2021 | cardiac arrest | University of Twente | Completed | Missed primary |
| — | NCT01930019 | Jun 2009 → Jul 2011 | obesity disorder | Military Institute od Medicine National Research Institute | Completed | No outcome recorded |
| — | NCT00379886 | Jan 2003 → Dec 2007 | depressive disorder | Rigshospitalet, Denmark | Unknown | No outcome recorded |
| Comparator or background therapy17 trials | ||||||
| Phase 1/2 | NCT01318044 Comparator | Jan → Apr 2011 | — | University Clinical Centre of Kosova | Unknown | No outcome recorded |
| Phase 3 | NCT03104140 Comparator | Apr 2017 → Apr 2018 | infectious disease with sepsis | Cairo University | Completed | No outcome recorded |
| Phase 3 | NCT00265616 Comparator | May 2006 → Mar 2010 | — | Brigham and Women's Hospital | Terminated | No outcome recorded Stop: Enrollment |
| Phase 3 | NCT00622570 Comparator | May 2002 → Jul 2007 | traumatic brain injury | Hospital Universitari Son Dureta | Terminated | No outcome recorded Stop: Enrollment |
| Phase 4 | NCT02504138 Background | Jun 2014 → May 2017 | liver failure | Yonsei University | Completed | No outcome recorded |
| Phase 4 | NCT01870011 Background | Dec 2013 → Nov 2014 | end stage renal failure | Yonsei University | Completed | No outcome recorded |
| Phase 4 | NCT01495949 Comparator | Dec 2011 → Dec 2013 | coronary artery disorder, heart valve disorder | Mahidol University | Completed | No outcome recorded |
| Phase 4 | NCT01518608 Background | Sep 2009 → Sep 2011 | — | Oslo University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT02377778 Comparator | Jan 2009 → Mar 2013 | infertility disorder | Aristotle University Of Thessaloniki | Completed | No outcome recorded |
| Phase 4 | NCT01474252 Background | Jul 2008 → Dec 2012 | — | Siriraj Hospital | Completed | No outcome recorded |
| Phase 4 | NCT00504894 Comparator | Mar 2007 → Nov 2013 | — | Weill Medical College of Cornell University | Terminated | No outcome recorded |
| — | NCT06485388 Comparator | Mar → Jul 2024 | — | Melike Cengiz | Completed | No outcome recorded |
| — | NCT02813044 Comparator | Jun 2016 → Jun 2018 | pituitary tumor | Yonsei University | Completed | No outcome recorded |
| — | NCT07033442 Comparator | Jul → Nov 2015 | ocular hypertension | Ataturk Training and Research Hospital | Completed | No outcome recorded |
| — | NCT02486926 Background | Nov 2012 → Jul 2013 | — | Hallym University Medical Center | Completed | No outcome recorded |
| — | NCT00767767 Comparator | Oct 2008 → May 2011 | phobic disorder | Weill Medical College of Cornell University | Completed | No outcome recorded |
| — | NCT00611767 Comparator | Nov 2005 → Apr 2012 | alcohol dependence | Yale University | Completed | No outcome recorded |
Evidence & citations 26 cited values
Every value below carries the sentence it was read from. 28 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Thiopental | “Step 3: Thiopental, initial dosage 12,5 mg/kg/hr for the first 6 hours followed by 5 mg/kg/hr for 6 hours” NCT02056236 ↗ |
| Known as | Farmotal | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | Hypnostan | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | Intraval sod | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | Leopental | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | Nesdonal | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | NSC-759557 | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | Penthiobarbital sodium | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | Pentothal | “Pentothal 4mg/kg Rocuronium 0.6 mg/kg” NCT01518608 ↗ |
| Known as | pentothal sodium | “In the inhalation anesthesia group, anesthesia is induced by pentothal sodium 4-6mg/kg and remifentanil 1 μg/kg, and then maintained with end-tidal sevoflurane concentration of...” NCT02813044 ↗ |
| Known as | Ravonal | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | Sodium pentothal | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | Sodium thiopental | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | Thionembutal | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | Thiopental ciii | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | Thiopental sodique | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | Thiopental Sodium | “Desflurane balanced anesthesia induced with thiopental sodium, remifentanil and atracurium and maintained with remifentanil target controlled infusion and desflurane inhalation” NCT02504138 ↗2“Desflurane balanced anesthesia induced with thiopental sodium, remifentanil and atracurium and maintained with remifentanil target controlled infusion and desflurane inhalation” NCT01870011 ↗ “Drug: Thiopental Sodium” NCT00142493 ↗ |
| Known as | Thiopentalum natricum | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | Thiopentobarbitone sodium | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | thiopentone | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01495949 ↗ |
| Known as | Thiopentone sodium | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | Tiopental de sodio | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Known as | Trapanal | ChEMBL registry synonym — accepted as the source's own label CHEMBL441 ↗ |
| Action | Activate | “GABAA receptor agonist thiopental” PMID 24273687 ↗ May 2012 |
| Modality | Small molecule | — CHEMBL441 ↗ |
| Route | Other | “as a continuous infusion” NCT00265616 ↗ |