Effects Of Anaesthesia on Intraocular Pressure in Robotic Prostate Surgery
Summary
Robot-assisted surgery is now commonly used to treat prostate cancer. This type of surgery, called robot-assisted prostatectomy, helps doctors operate more precisely and allows patients to heal faster. But there are some special things to be careful about during these surgeries. During the operation, the patient is placed in a steep head-down position for a long time. Staying in this position for a long period can cause the pressure inside the eyes-called intraocular pressure (IOP)-to go up. High eye pressure can be risky, especially for people who already have eye problems. This study looked at different types of anesthesia used during robotic prostate surgery to see how they affect eye pressure. The goal was to find out which type of anesthesia causes less of an increase in eye pressure.
Timeline
- Start
- 2015-07-23
- Primary completion
- 2015-11-17
- Completion
- 2015-12-24
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propofol | Small molecule | 50 ug/kg | Intravenous |
| Comparator | Propofol | Small molecule | 150 ug/kg | Intravenous |
| Comparator | Sevoflurane | Other / unclassified | 2 % | Inhaled |
| Comparator | Sevoflurane | Other / unclassified | 3 % | Inhaled |
| Comparator | Atropine | Other / unclassified | 0.4 mg | Intravenous |
| Comparator | Atropine | Other / unclassified | 0.5 mg | Intravenous |
| Comparator | Ephedrine | Small molecule | 0.1 mg/kg | Intravenous |
| Comparator | Lidocaine | Other / unclassified | 1 mg/kg | Intravenous |
| Comparator | Lidocaine | Other / unclassified | 1.5 mg/kg | Intravenous |
| Comparator | Neostigmine | Other / unclassified | 0.04 mg/kg | Intravenous |
| Comparator | Remifentanil | Small molecule | 0.05 ug/kg | Intravenous |
| Comparator | Remifentanil | Small molecule | 0.25 ug/kg | Intravenous |
| Comparator | Rocuronium | Other / unclassified | 0.15 mg/kg | Intravenous |
| Comparator | Thiopental | Small molecule | 4 mg/kg | Intravenous |
| Comparator | Thiopental | Small molecule | 6 mg/kg | Intravenous |