drugset / Trial / NCT00967291

Mitomycin C and Ifosfamide in Treating Patients With Metastatic Pancreatic Cancer

NCT00967291 ↗

Phase 2 Terminated 21 enrolled IRCCS San Raffaele
NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Drugs used in chemotherapy, such as mitomycin C and ifosfamide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving mitomycin C together with ifosfamide works in treating patients with metastatic pancreatic cancer.

Timeline

Start
2006-03
Primary completion
2008-06
Completion
2008-06

Outcome

Outcome not reported

Stopped: “lack of activity and G3-4 toxicity at interim analysis”

Drugs

EvaluationDrugModalityDoseRoute
Subject Ifosfamide Small molecule 2500 mg/m2 Intravenous
Subject Mitomycin C Other / unclassified 8 mg/m2 Intravenous