drugset / Trial / NCT00978263
Comparison of Glargine and Oral Antidiabetic Drugs (OADs) in Newly Diagnosed Type 2 Diabetes
RandomizedParallel-groupOpen-labelTreatment
Summary
The investigators designed this prospective, randomized control study to compare the efficacy and safety between the basal insulin glargine therapy and metformin-based OADs after correction of the glucose toxicity with a short period of intensive insulin therapy.
Timeline
- Start
- 2009-02
- Primary completion
- 2011-12
- Completion
- 2012-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Gliclazide | Small molecule | — | Oral |
| Subject | Glimepiride | Small molecule | — | Oral |
| Subject | Metformin | Small molecule | 850 mg | Oral |
| Subject | insulin glargine | Protein / enzyme biologic | — | Other |