drugset / Trial / NCT00982254
Oral Insulin: A Comparison With Subcutaneous Regular Human Insulin in Patients With Type 2 Diabetes
Phase 1
Completed
10 enrolled
Profil Institute for Metabolic Research GmbH
Emisphere Technologies, Inc. · collab
RandomizedCrossoverOpen-labelTreatment
Summary
This study compared the pharmacokinetic and pharmacodynamic properties of an oral insulin formulation with that of a standard subcutaneous injection of regular human insulin.
Timeline
- Start
- 2001-10
- Primary completion
- 2001-11
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Insulin | Protein / enzyme biologic | 15 iu | Oral |
| Subject | Insulin | Protein / enzyme biologic | 150 iu | Oral |
| Subject | Insulin | Protein / enzyme biologic | 300 iu | Oral |
| Background | 4-CNAB | Small molecule | 200 mg | Oral |
| Background | 4-CNAB | Small molecule | 400 mg | Oral |