drugset / Trial / NCT00982982

Effects of Delta-9-THC and Iomazenil in Healthy Humans

NCT00982982

Phase 0 Completed 17 enrolled Yale University
RandomizedCrossoverQuadruple-blindBasic science

Summary

The study aims to examine the combined effects of delta-9-tetrahydrocannabinol (∆-9-THC or THC) and iomazenil on thinking, perception, mood, memory, attention, and electrical activity of the brain (EEG). THC is the active ingredient of marijuana, cannabis, "ganja", or "pot". Iomazenil is a drug that works opposite to drugs like valium. The purpose of this study is to determine whether the administration of iomazenil will alter the effects of THC.

Timeline

Start
2009-02-11
Primary completion
2013-02-22
Completion
2013-02-22

Drugs

EvaluationDrugModalityDoseRoute
Comparator Iomazenil Small molecule 3.7 ug/kg Intravenous
Comparator delta-9-tetrahydrocannabinol Other / unclassified 0.015 mg/kg Intravenous

Indications