drugset / Trial / NCT00997035
The Mycotic Ulcer Treatment Trial II: A Randomized Trial Comparing Oral Voriconazole vs Placebo
Phase 3
Completed
240 enrolled
University of California, San Francisco
Aravind Eye Hospitals, India · collabBharatpur Eye Hospital · collabDartmouth-Hitchcock Medical Center · collabLumbini Eye Institute and Research Centre · collabNational Eye Institute (NEI) · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to determine if the addition of oral voriconazole to topical treatment regimens results in lower rates of perforation in severe fungal corneal ulcers.
Timeline
- Start
- 2010-05
- Primary completion
- 2016-01
- Completion
- 2016-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Voriconazole | Small molecule | 1 % | Topical |
| Comparator | Voriconazole | Small molecule | 100 mg | Topical |
| Comparator | Voriconazole | Small molecule | 150 mg | Topical |
| Comparator | Voriconazole | Small molecule | 200 mg | Topical |