drugset / Trial / NCT01000337

Markers of Liver Apoptosis After Anesthesia With Sevoflurane or Propofol

NCT01000337 ↗

Completed 67 enrolled University of Athens
RandomizedParallel-groupSingle-blindOther

Summary

Anesthesia may affect the function of vital organs. Liver is one of them. The investigator's hypothesis is that intravenous or inhalation anesthesia does not impair liver function as assessed by more elegant tests like markers indicating liver apoptosis. In the present randomized prospective trial female patients scheduled for mastectomy or thyroidectomy will receive inhalation or total intravenous anesthesia and markers for liver dysfunction will be determined.

Timeline

Start
2009-10
Primary completion
2011-11
Completion
2012-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Propofol Small molecule 6 mg/kg Intravenous
Comparator Sevoflurane Other / unclassified 2 % Inhaled

Indications