drugset / Trial / NCT01004874
Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma
NaSingle-groupOpen-labelTreatment
Summary
This is a phase II study of the combination of radiation therapy, temozolomide and Avastin followed by Avastin, temozolomide, and topotecan in grade IV malignant glioma patients.
Timeline
- Start
- 2009-12-30
- Primary completion
- 2012-07
- Completion
- 2021-11-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bevacizumab | Monoclonal antibody | 10 mg/kg | — |
| Subject | Temozolomide | Small molecule | 150 mg/m2 | — |
| Subject | Topotecan | Small molecule | 1.5 mg/m2 | — |
| Subject | Topotecan | Small molecule | 2 mg/m2 | — |