drugset / Trial / NCT01005433

Dexmedetomidine for Cesarean Delivery

NCT01005433

Phase 1 Completed 68 enrolled King Faisal University
RandomizedParallel-groupDouble-blindPrevention

Summary

Regional anesthesia has become the anesthetic of choice for cesarean section in most countries; however, some women still prefer general anesthesia techniques. There are many trials for the pharmacological modifications of the sympathetic response to surgery, including opioids, tenoxicam, ketorolac, lidocaine and paracetamol. However, opioid administration to the mother before delivery has adverse neonatal effects. This research is a novel trial on the use of dexmedetomidine for suppression of the hemodynamic and hormonal responses of cesarean delivery.

Timeline

Start
2009-12
Primary completion
2011-10
Completion
2011-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexmedetomidine Other / unclassified 0.2 ug/kg Intravenous
Comparator Dexmedetomidine Other / unclassified 0.4 ug/kg Intravenous
Comparator Dexmedetomidine Other / unclassified 0.6 ug/kg Intravenous

Indications

No indication recorded.