drugset / Trial / NCT01005680
A Study Comparing Two Different Chemotherapy Types in Chinese Patients With Advanced Non Small Cell Lung Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to compare the efficacy and safety of two different chemotherapy types in the first line treatment of advanced Non-Small Cell Lung Cancer (NSCLC).
Timeline
- Start
- 2009-11
- Primary completion
- 2012-11
- Completion
- 2012-11
Outcome
Missed primary endpoint
registry Pemetrexed Plus Cisplatin (PC) vs Gemcitabine Plus Cisplatin (GC); p = 0.822; Hazard Ratio (HR) 1.03 (95% CI 0.77 to 1.39) NCT01005680 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cisplatin | Other / unclassified | 75 mg/m2 | Intravenous |
| Comparator | Gemcitabine | Small molecule | 1250 mg/m2 | Intravenous |
| Subject | Pemetrexed | Small molecule | 500 mg/m2 | Intravenous |