The Pharmacologic Profile of Sodium Thiosulfate in Renal Failure and Healthy Volunteers

Completed 19 enrolled Insel Gruppe AG, University Hospital Bern

Non-randomizedSingle-groupOpen-labelTreatment

Summary

The pharmacokinetics of sodium thiosulfate in humans with different degrees of renal failure and in healthy volunteers will be after two single shot applications.

Timeline

Start: 2009-09
Primary completion: 2010-08
Completion: 2010-08

Publications

Farese S, Stauffer E, Kalicki R, Hildebrandt T, Frey BM, Frey FJ, Uehlinger DE, Pasch A. Sodium thiosulfate pharmacokinetics in hemodialysis patients and healthy volunteers. Clin J Am Soc Nephrol. 2011 Jun;6(6):1447-55. doi: 10.2215/CJN.10241110. Epub 2011 May 12.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Sodium Thiosulfate	Diagnostic / imaging agent	6 g	Intravenous

The Pharmacologic Profile of Sodium Thiosulfate in Renal Failure and Healthy Volunteers

Summary

Timeline

Publications

Drugs

Indications