drugset / Trial / NCT01009983

Paclitaxel, Carboplatin, and Panitumumab in Treating Patients With Metastatic Breast Cancer

NCT01009983 ↗

Phase 2 Terminated 14 enrolled Wake Forest University Health Sciences
NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as panitumumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Other find tumor cells and help kill them or carry tumor-killing substances to them. Giving panitumumab together with paclitaxel and carboplatin may be a better way to block tumor growth. PURPOSE: This phase II trial is studying the side effects and how well paclitaxel and carboplatin together with panitumumab works in treating patients with metastatic triple negative breast cancer.

Timeline

Start
2010-03
Primary completion
2013-07
Completion
2013-12

Outcome

Outcome not reported

Stopped (Enrollment): “Slow accrual”

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule — Intravenous
Subject Paclitaxel Small molecule — Intravenous
Subject Panitumumab Monoclonal antibody — Intravenous