drugset / Trial / NCT01010399

Boosted Lexiva With Lovaza Adjunctive Therapy in Hypertriglyceridemic, HIV-Infected Subjects

NCT01010399

Phase 4 Completed 36 enrolled Felizarta, Franco, M.D. GlaxoSmithKline · collab
NaSingle-groupOpen-labelTreatment

Summary

In subjects on boosted protease inhibitor (PI)-regimens who have elevated triglycerides, a switch to fosamprenavir/ritonavir once daily followed by the addition of Lovaza will result in 30% of patients achieving a reduction in fasting triglycerides \< 200 mg /dL while maintaining virologic suppression.

Timeline

Start
2009-09
Primary completion
2010-11
Completion
2010-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Fosamprenavir Small molecule 1400 mg
Background Ritonavir Other / unclassified 100 mg