drugset / Trial / NCT01015066
Comparison of Buprenorphine/Naloxone With Naltrexone in Opioid Dependent Adolescents
RandomizedParallel-groupOpen-labelTreatment
Summary
This study is designed to determine the relative effectiveness of buprenorphine/naloxone (Suboxone) pharmacotherapy versus naltrexone pharmacotherapy for treatment retention, relapse prevention and opioid craving reduction among opioid-dependent adolescents and young adults. The investigators hypothesize that naltrexone treatment is as effective as buprenorphine/naloxone for these treatment outcomes.
Timeline
- Start
- 2009-11
- Primary completion
- 2014-06
- Completion
- 2014-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Buprenorphine | Other / unclassified | 2 mg | Other |
| Comparator | Naloxone | Small molecule | 0.5 mg | Other |
| Subject | Naltrexone | Small molecule | 50 mg | Oral |