drugset / Trial / NCT01017094

Pin Site Infection Prevention for Open Tibial Fracture

NCT01017094

Phase 3 Completed 30 enrolled Prince of Songkla University
RandomizedParallel-groupSingle-blindTreatment

Summary

This study aimed to compare the efficacy of pin-tract infection prevention between silversulfadiazine and dry dressing. Methods: 30 patients with an open tibial fracture admitted to Songklanagarind hospital from September 2007 to June 2008 and treated by emergency debridement and external fixation were randomized into two groups, one treated with silversulfadiazine for infection prophylaxis (15) and a control group treated with dry dressing only (15). All patients were followed until the external fixator was removed. Pin-site infections were assessed and graded at each follow-up visit by an orthopaedist blinded to the mode of treatment. A culture from the pin site was done if an infection occurred.

Timeline

Start
2007-09
Primary completion
2008-06
Completion
2009-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Silver Sulfadiazine Small molecule Other

Indications