Antiemetic Efficacy and Safety of Dexamethasone in Obstetric Surgical Patients

Completed 250 enrolled Makerere University

RandomizedParallel-groupQuadruple-blindPrevention

Summary

This is a randomised controlled double blinded clinical trial to determine the antiemetic efficacy and safety of either 8 mg of dexamethasone or normal saline (placebo) given 1 hour before induction of either spinal or general anaesthesia in 2 arms (of 150 each).

Timeline

Start: 2010-01
Primary completion: 2010-03
Completion: 2010-03

Publications

Griffiths JD, Gyte GM, Popham PA, Williams K, Paranjothy S, Broughton HK, Brown HC, Thomas J. Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section. Cochrane Database Syst Rev. 2021 May 18;5(5):CD007579. doi: 10.1002/14651858.CD007579.pub3.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Dexamethasone	Small molecule	8 mg	—

Indications

No indication recorded.