drugset / Trial / NCT01031849

Analysis of Changes in Adipose Tissue of Patients With Lipoatrophy HIV Infection Treated With Nucleoside Thymidine, After Switching to Monotherapy With Lopinavir / Ritonavir

NCT01031849

Phase 4 Terminated 7 enrolled Ines Perez
NaSingle-groupOpen-label

Summary

The objective is to analyse the changes in the adipose tissue hystological features and the adipogenesis gene expression and related to inflammation after 48 and 96 weeks after the change from AZT+3TC+ABC (Trizivir®) to a monotherapy treatment with LPV/r (Kaletra®)

Timeline

Start
2010-02
Primary completion
2012-10
Completion
2012-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Lopinavir Other / unclassified 400 mg
Subject Ritonavir Other / unclassified 100 mg