Local Anesthetics New Formulations: From Development to Clinical Tests

Phase 1 Completed 30 enrolled University of Campinas, Brazil Fundação de Amparo à Pesquisa do Estado de São Paulo · collab

RandomizedCrossoverTriple-blindHealth-services research

Summary

This blinded cross-over study aim to evaluate the efficacy and the pharmacokinetics of a previously reported liposome-encapsulated mepivacaine formulations.

Timeline

Start: 2007-05
Primary completion: —
Completion: 2008-05

Publications

Tofoli GR, Cereda CM, Groppo FC, Volpato MC, Franz-Montan M, Ranali J, de Araujo DR, de Paula E. Efficacy of liposome-encapsulated mepivacaine for infiltrative anesthesia in volunteers. J Liposome Res. 2011 Mar;21(1):88-94. doi: 10.3109/08982104.2010.483596. Epub 2010 May 20.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Epinephrine	Other / unclassified	—	Other
Subject	Mepivacaine	Other / unclassified	2 %	Other
Subject	Mepivacaine	Other / unclassified	3 %	Other

Indications

No indication recorded.