drugset / Trial / NCT01042288

Carboplatin, Pemetrexed, and Panitumumab in Patients With Advanced Non-Squamous K-ras Wild Type NSCLC

NCT01042288 ↗

Phase 2 Completed 70 enrolled SCRI Development Innovations, LLC Amgen · collab
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this multicenter, Phase II trial is to examine the role of a well-tolerated novel agent, panitumumab, in combination with a modern platinum doublet regimen using carboplatin and pemetrexed, in patients with advanced non-squamous wild type K-ras non-small-cell lung cancer (NSCLC). If this treatment proves to be well tolerated and associated with efficacy, this would provide rationale for further randomized studies.

Timeline

Start
2010-06
Primary completion
2014-12
Completion
2015-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Panitumumab Monoclonal antibody 9 mg/kg Intravenous
Background Carboplatin Small molecule 6 unknown Intravenous
Background Pemetrexed Small molecule 500 mg/m2 Intravenous