drugset / Trial / NCT01044342
A Healthy Volunteer Study to Evaluate Reversibility of Induced Impairment of Cognition
RandomizedCrossoverDouble-blindBasic science
Summary
The purpose of this study is to determine if cognitive impairment induced by scopolamine is reversed using donepezil and/or AZD1446 as compared to placebo, as assessed by electroencephalogram (EEG) measures.
Timeline
- Start
- 2009-12
- Primary completion
- 2010-04
- Completion
- 2010-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | AZD1446 | Small molecule | 10 mg | Oral |
| Subject | AZD1446 | Small molecule | 80 mg | Oral |
| Comparator | Donepezil | Small molecule | 5 mg | Oral |
Indications
No indication recorded.