drugset / Trial / NCT01052038

Post Operative Sore Throat and Dexamethasone

NCT01052038 ↗

Phase 4 Completed 120 enrolled Northwestern University
RandomizedParallel-groupTriple-blindPrevention

Summary

Sore throat is a common postoperative complaint that can lead to morbidity and patient dissatisfaction . The incidence of sore throat has been reported to be between 6% and 90% even under optimal intubating conditions. There are several factors that have been shown to contribute to postoperative sore throat such as patient related factors, type of anesthesia and type of surgery. Corticosteroids are also commonly used in the perioperative period to potentiate analgesics and as antiemetics. The preoperative administration of dexamethasone can decrease the incidence and severity of postoperative sore throat which is rated by patients as one of the most undesirable outcomes in the postoperative period.

Timeline

Start
2010-01
Primary completion
2010-09
Completion
2010-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexamethasone Small molecule 0.05 mg/kg —
Comparator Dexamethasone Small molecule 0.1 mg/kg —

Indications