drugset / Trial / NCT01052194
A 12-week Study of 4 Doses of VX-509 in Subjects With Active Rheumatoid Arthritis
RandomizedParallel-groupDouble-blindTreatment
Summary
This study is designed to evaluate safety and assess initial efficacy of VX-509, a JAK3 inhibitor, for treatment of subjects with active RA. This study will assess the clinical response of 4 doses of VX-509 compared to placebo when administered for 12 weeks to patients with active RA. The study will also evaluate the safety and tolerability of VX-509 compared to placebo when administered for 12 weeks to subjects with active RA.
Timeline
- Start
- 2010-02
- Primary completion
- 2011-07
- Completion
- 2011-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | decernotinib | Small molecule | 25 mg | — |
| Subject | decernotinib | Small molecule | 50 mg | — |
| Subject | decernotinib | Small molecule | 100 mg | — |
| Subject | decernotinib | Small molecule | 150 mg | — |