drugset / Trial / NCT01054768
Antioxidant Therapy to Reduce Inflammation in Sickle Cell Disease
Phase 2
Completed
37 enrolled
UCSF Benioff Children's Hospital Oakland
National Center for Complementary and Integrative Health (NCCIH) · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to determine whether alpha-lipoic acid and acetyl-L-carnitine will lower systemic inflammation in patients with Sickle Cell Disease by reducing oxidative stress, which will result in a decrease in the frequency of vaso-occlusive pain episodes and improve their quality of life.
Timeline
- Start
- 2009-08
- Primary completion
- 2013-04
- Completion
- 2013-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acetylcarnitine | Small molecule | — | — |
| Subject | alpha-lipoic acid | Small molecule | — | — |