drugset / Trial / NCT01056237

Long-Term Study of Multi-target Therapy as Maintenance Treatment for Lupus Nephritis

NCT01056237

Completed 206 enrolled Zhi-Hong Liu, M.D.
RandomizedParallel-groupOpen-labelTreatment

Summary

An multi-site, randomized, prospective study to compare the efficacy and safety of multi-target therapy as continuous induction and maintenance treatment versus CTX- Aza therapy.

Timeline

Start
2010-02
Primary completion
2013-06
Completion
2013-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Azathioprine Small molecule 1 mg/kg
Comparator Azathioprine Small molecule 2 mg/kg
Subject Mycophenolate Mofetil Small molecule 0.5 g
Subject Mycophenolate Mofetil Small molecule 0.75 g
Subject Tacrolimus Small molecule 1 mg
Subject Tacrolimus Small molecule 3 mg

Indications