drugset / Trial / NCT01058005

Study Evaluating Rebif, Copaxone, and Tysabri for Active Multiple Sclerosis

NCT01058005

Phase 3 Terminated 84 enrolled Biogen Elan Pharmaceuticals · collab
RandomizedParallel-groupOpen-label

Summary

This was a multicenter, randomized, open-label, parallel-group, active-controlled study. Prior to randomization, participants were to have been treated with glatiramer acetate or interferon β-1a (44 μg). Participants were to be randomized to receive natalizumab, interferon β-1a 44 μg, or glatiramer acetate.

Timeline

Start
2010-03
Primary completion
2012-04
Completion
2012-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Glatiramer Acetate Small molecule 20 mg Subcutaneous
Comparator Interferon beta-1a Protein / enzyme biologic 44 ug Subcutaneous
Subject natalizumab Monoclonal antibody 300 mg Intravenous