drugset / Trial / NCT01058005
Study Evaluating Rebif, Copaxone, and Tysabri for Active Multiple Sclerosis
RandomizedParallel-groupOpen-label
Summary
This was a multicenter, randomized, open-label, parallel-group, active-controlled study. Prior to randomization, participants were to have been treated with glatiramer acetate or interferon β-1a (44 μg). Participants were to be randomized to receive natalizumab, interferon β-1a 44 μg, or glatiramer acetate.
Timeline
- Start
- 2010-03
- Primary completion
- 2012-04
- Completion
- 2012-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Glatiramer Acetate | Small molecule | 20 mg | Subcutaneous |
| Comparator | Interferon beta-1a | Protein / enzyme biologic | 44 ug | Subcutaneous |
| Subject | natalizumab | Monoclonal antibody | 300 mg | Intravenous |