drugset / Trial / NCT01062568
The Adrenal Contribution to Androgen Production in Girls During Puberty
Non-randomizedSingle-groupOpen-labelDiagnostic
Summary
In girls with elevated androgens the precise source of androgen excess throughout puberty and early adolescence has not been carefully examined. The investigators propose to examine whether the adrenal gland produces the majority of androgens during puberty by studying the differences in androgen responses to adrenocorticotropin hormone (ACTH) administration in normal weight (NW) and obese (OB) girls ages 7-18. The investigators' analyses will compare steroid changes before and 60 min after ACTH administration in NW and OB girls.
Timeline
- Start
- 2010-02
- Primary completion
- 2014-07
- Completion
- 2014-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Adrenocorticotropin | Protein / enzyme biologic | 0.25 mg | Intravenous |
| Background | Dexamethasone | Small molecule | — | Oral |
Indications
No indication recorded.